Author

M. F. Kearney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

J. W. Mellors· 3 shared A. Wiegand· 2 shared D. Wells· 2 shared F. Maldarelli· 2 shared J. M. Coffin· 2 shared S. H. Hughes· 2 shared W. Shao· 2 shared X. Wu· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

J. W. Mellors

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells

H. Batra, J. Zhu, S. Jain, N. Ananthaswamy, M. Mahalingam, P. Tao, C. Lange, S. Hill, C. Zhong, M. F. Kearney, H. Hu, F. Maldarelli, V. B. Rao

The paper shows that CD4-targeted bacteriophage T4 nanoparticles reactivate HIV-1 latency in CD4+ T-cells without global activation or cytokine storm.

bioRxiv · Jul 20, 2021 · PreprintImmunology

Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy

J. M. Coffin, M. Bale, D. Wells, S. Guo, B. Luke, J. M. Zerbato, M. D. Sobolewski, T. Sia, W. Shao, X. Wu, F. Maldarelli, M. F. Kearney, J. W. Mellors, S. H. Hughes

The paper compares HIV integration site distributions in vivo and in vitro to assess the role of oncogene integration in viral persistence during ART.

bioRxiv · Nov 25, 2020Microbiology

Early Emergence and Long-Term Persistence of HIV-Infected T Cell Clones in Children

M. J. Bale, M. G. Katusiime, D. Wells, X. Wu, J. Spindler, E. K. Halvas, J. C. Cyktor, A. Wiegand, W. Shao, M. F. Cotton, S. H. Hughes, J. W. Mellors, J. M. Coffin, G. U. Van Zyl, M. F. Kearney

This study identifies early emergence and long-term persistence of HIV-infected T cell clones in children on antiretroviral therapy, with proviral integration in proto-oncogenes.

bioRxiv · Sep 15, 2020Microbiology

Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations

Y. Hikichi, R. Van Duyne, P. Pham, J. L. Groebner, A. Wiegand, J. W. Mellors, M. F. Kearney, E. O. Freed

This study shows that HIV-1 envelope glycoprotein mutations can confer broad antiretroviral resistance through cell-cell transmission and structural changes, independent of target-gene mutations.

bioRxiv · Aug 6, 2020Microbiology