Author

D. Wells

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:clustering· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:deep learning· 1

Frequent Co-Authors

J. M. Coffin· 2 shared J. W. Mellors· 2 shared M. F. Kearney· 2 shared S. H. Hughes· 2 shared W. Shao· 2 shared X. Wu· 2 shared A. C. Banyard· 1 shared A. Chow· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

J. M. Coffin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade

J. A. Pai, A. Chow, J. Sauter, M. Mattar, H. Rizvi, H. J. Woo, N. Shah, F. Uddin, A. Quintanal-Villalonga, J. M. Chan, P. Manoj, V. Allaj, M. Baine, J. E. Chaft, A. J. Plodkowski, , M. D. Hellmann

This study uses scTCR/RNA-seq to analyze T cell dynamics in lung cancer patients before and after ICB, finding regional heterogeneity and clonal persistence associated with clinical responses.

bioRxiv · Sep 27, 2021 · PreprintImmunology

Establishment of pan-Influenza A (H1-H18) and pan-Influenza B (pre-split, Vic/Yam) Pseudotype Libraries for efficient vaccine antigen selection

J. M. Del Rosario, K. da Costa, B. Asbach, F. Ferrara, M. Ferrari, D. Wells, G. S. Mann, V. O. Ameh, C. T. Sabeta, A. C. Banyard, R. Kinsley, S. D. Scott, R. Wagner, J. L. Heeney, G. W. Carnell, N. J. Temperton

The paper develops HA pseudotype libraries for Influenza A and B to improve vaccine antigen selection and neutralization assay capabilities.

bioRxiv · May 20, 2021 · PreprintImmunology

Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy

J. M. Coffin, M. Bale, D. Wells, S. Guo, B. Luke, J. M. Zerbato, M. D. Sobolewski, T. Sia, W. Shao, X. Wu, F. Maldarelli, M. F. Kearney, J. W. Mellors, S. H. Hughes

The paper compares HIV integration site distributions in vivo and in vitro to assess the role of oncogene integration in viral persistence during ART.

bioRxiv · Nov 25, 2020Microbiology

Early Emergence and Long-Term Persistence of HIV-Infected T Cell Clones in Children

M. J. Bale, M. G. Katusiime, D. Wells, X. Wu, J. Spindler, E. K. Halvas, J. C. Cyktor, A. Wiegand, W. Shao, M. F. Cotton, S. H. Hughes, J. W. Mellors, J. M. Coffin, G. U. Van Zyl, M. F. Kearney

This study identifies early emergence and long-term persistence of HIV-infected T cell clones in children on antiretroviral therapy, with proviral integration in proto-oncogenes.

bioRxiv · Sep 15, 2020Microbiology