Author

J. McFadden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

H. Wu· 2 shared K. Borah· 2 shared A. Theorell· 1 shared B. Bonde· 1 shared D. Beste· 1 shared D. Williams· 1 shared I. W. Nyinoh· 1 shared J. Kearney· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

H. Wu

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3 papers

Recent·Most cited

GSMN-ML- a genome scale metabolic network reconstruction of the obligate human pathogen Mycobacterium leprae

K. Borah, J. Kearney, R. Banerjee, P. Vats, H. Wu, S. Dahale, S. Manjari, R. Joshi, B. Bonde, O. Ojo, R. Lahiri, D. Williams, J. McFadden

This paper reconstructs a genome-scale metabolic network for Mycobacterium leprae to study its metabolism and identify potential drug targets.

bioRxiv · Oct 25, 2019Microbiology

A mixed nitrogen diet and compartmentalized utilization for Mycobacterium tuberculosis replicating in host cells: results of a systems-based analysis

K. Borah, M. Beyss, A. Theorell, H. Wu, P. Basu, T. Mendum, K. Noh, D. Beste, J. McFadden

This study investigates nitrogen metabolism in intracellular Mycobacterium tuberculosis using a systems-based approach, revealing compartmentalized utilization of host-derived nitrogen sources.

bioRxiv · Feb 6, 2019 · PreprintMicrobiology

Spontaneous mutations conferring antibiotic resistance to antitubercular drugs at a range of concentrations in Mycobacterium smegmatis

I. W. Nyinoh, J. McFadden

This study estimates mutation rates for antibiotic resistance in Mycobacterium smegmatis at various drug concentrations using fluctuation assays and multiple analytical methods.

bioRxiv · Apr 6, 2018Microbiology