Author

J. Megret

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 4 Assay:scRNA-seq· 4 Research Focus:differential expression· 3 Research Focus:clustering· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Roeser· 4 shared A. Sokal· 4 shared A. Vandenberghe· 4 shared C.-A. Reynaud· 4 shared E. Crickx· 4 shared F. A. Rey· 4 shared F. Noizat-Pirenne· 4 shared G. Barba-Spaeth· 4 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

A. Roeser

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals.

A. Sokal, G. Barba-Spaeth, L. Hunault, I. Fernandez, M. Broketa, A. Meola, S. Fourati, I. Azzaoui, A. Vandenberghe, P. Lagouge-Roussey, M. Broutin, A. Roeser, M. Bouvier-Alias, E. Crickx, L. Languille, , P. Chappert

This study shows that Omicron BA.1 breakthrough infection in vaccinated individuals leads to long-term remodeling of memory B cells, enhancing neutralizing breadth and potency against common and BA.1 epitopes but not BA.5.

bioRxiv · Jan 27, 2023 · PreprintImmunology

Immune escape of SARS-CoV-2 Omicron variant from mRNA vaccination-elicited RBD-specific memory B cells.

A. Sokal, M. Broketa, A. Meola, G. Barba-Spaeth, I. Fernandez, S. Fourati, I. Azzaoui, A. de La Selle, A. Vandenberghe, A. Roeser, M. Bouvier-Alias, E. Crickx, L. Languille, M. Michel, B. Godeau, , M. Mahevas

The paper assesses how well mRNA vaccine-induced memory B cells recognize the Omicron variant of SARS-CoV-2 and finds that Omicron evades recognition more than previous variants.

bioRxiv · Dec 21, 2021 · PreprintImmunology

Memory B cells control SARS-CoV-2 variants upon mRNA vaccination of naive and COVID-19 recovered individuals.

A. Sokal, G. Barba-Spaeth, I. Fernandez, M. Broketa, I. Azzaoui, A. de La Selle, A. Vandenberghe, S. Fourati, A. Roeser, A. Meola, M. Bouvier-Alias, E. Crickx, L. Languille, M. Michel, B. Godeau, , M. Mahevas

The study compares memory B cell responses in naive and recovered individuals after mRNA vaccination, showing enhanced expansion and neutralization against variants in recovered patients.

bioRxiv · Jun 17, 2021 · PreprintImmunology

Maturation and persistence of the anti-SARS-CoV-2 memory B cell response.

A. Sokal, P. Chappert, A. Roeser, G. Barba-Spaeth, S. Fourati, I. Azzaoui, A. Vandenberghe, I. Fernandez, M. Bouvier-Alias, E. Crickx, A. Beldi Ferchiou, S. Hue, L. Languille, S. Baloul, F. Noizat-Pirenne, , M. Mahevas

This study tracks the maturation of SARS-CoV-2-specific memory B cells over 6 months, showing their persistence and mutation accumulation.

bioRxiv · Nov 17, 2020Immunology

Direct contribution of skeletal muscle mesenchymal progenitors to bone repair

A. Julien, A. Kanagalingam, J. Megret, M. Luka, M. Menager, F. Relaix, C. COLNOT

This study shows skeletal muscle mesenchymal progenitors contribute to bone repair by first forming fibrous tissue and then supporting cartilage and bone formation, but fail to do so in polytrauma leading to impaired healing.

bioRxiv · Sep 8, 2020Physiology