Author

L. Hunault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

B. Dupuy· 3 shared P. England· 3 shared B. Iannascoli· 2 shared C. Guo· 2 shared D. Sterlin· 2 shared E. Auria· 2 shared G. Gorochov· 2 shared L. Macdonald· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

B. Dupuy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A monoclonal antibody collection for C. difficile typing

L. Hunault, P. England, F. Barbut, B. Iannascoli, O. Godon, F. Dejardin, C. Thomas, B. Dupuy, C. Guo, L. Macdonald, G. Gorochov, D. Sterlin, P. Bruhns

The paper develops a monoclonal antibody collection targeting C. difficile strains to improve research on clinically relevant ribotypes.

bioRxiv · Sep 21, 2023 · PreprintImmunology

Anti-S-layer monoclonal antibodies impact Clostridioides difficile physiology

L. Hunault, E. Auria, P. England, J. Deschamps, R. Briandet, V. Kremer, B. Iannascoli, L. Vidal-Maison, C. Guo, L. Macdonald, S. Pechine, C. Deneve-Larrazet, B. Dupuy, G. Gorochov, P. Bruhns, D. Sterlin

This study identifies monoclonal antibodies targeting C. difficile's S-layer protein, revealing both protective and detrimental effects on bacterial physiology.

bioRxiv · Sep 21, 2023 · PreprintMicrobiology

Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals.

A. Sokal, G. Barba-Spaeth, L. Hunault, I. Fernandez, M. Broketa, A. Meola, S. Fourati, I. Azzaoui, A. Vandenberghe, P. Lagouge-Roussey, M. Broutin, A. Roeser, M. Bouvier-Alias, E. Crickx, L. Languille, , P. Chappert

This study shows that Omicron BA.1 breakthrough infection in vaccinated individuals leads to long-term remodeling of memory B cells, enhancing neutralizing breadth and potency against common and BA.1 epitopes but not BA.5.

bioRxiv · Jan 27, 2023 · PreprintImmunology

The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile

E. Auria, L. Hunault, P. ENGLAND, M. Monot, J. Pipoli Da Fonseca, M. Matondo, M. Duchateau, Y. D. Tremblay, B. Dupuy

This study identifies CD1687 as a DNA-binding lipoprotein required for DCA-induced biofilm formation in C. difficile by promoting cell-matrix interactions through eDNA binding.

bioRxiv · Nov 29, 2022 · PreprintMicrobiology