Author

J. Op de Beeck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:benchmarking· 2 Approach:benchmark study· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

P. Jacobs· 4 shared K. Mechtler· 3 shared G. Desmet· 2 shared K. Stejskal· 2 shared A. Argentini· 1 shared A. Staes· 1 shared F. Impens· 1 shared G. Duernberger· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiochemistry

P. Jacobs

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4 papers

Recent·Most cited

Deep proteome profiling with reduced carry over using superficially porous microfabricated nanoLC columns

K. Stejskal, J. Op de Beeck, M. Matzinger, G. Duernberger, O. Boychenko, P. Jacobs, K. Mechtler

This paper evaluates prototype nanoLC columns for improved proteome profiling, finding increased protein group and peptide identification with reduced carry over and methionine oxidation.

bioRxiv · Nov 28, 2021 · PreprintBiochemistry

Ultra-sensitive nanoLC-MS of sub nanogram protein samples using second generation micro pillar array LC technology with Orbitrap Exploris 480 and FAIMS PRO

K. Stejskal, J. Op de Beeck, G. Dürnberger, P. Jacobs, K. Mechtler

This paper benchmarks ultra-sensitive proteomics methods using micro pillar array LC and FAIMS PRO, achieving detection of 1486 protein groups from 250 pg of HeLa tryptic digest.

bioRxiv · Feb 10, 2021Cell Biology

A well-ordered nanoflow LC-MS/MS approach for proteome profiling using 200 cm long micro pillar array columns

J. Op De Beeck, J. Pauwels, N. Van Landuyt, P. Jacobs, W. De Malsche, G. Desmet, A. Argentini, A. Staes, L. Martens, F. Impens, K. Gevaert

This paper introduces a long micro pillar array column for proteome profiling, showing improved protein identification and peak resolution compared to conventional columns.

bioRxiv · Jul 1, 2019 · PreprintBiochemistry

Improved Sensitivity in Low-Input Proteomics using Micro-Pillar Array-based Chromatography

J. Stadlmann, O. Hudecz, G. Krssakova, G. Van Raemdonck, J. Op De Beeck, G. Desmet, J. M. Penninger, P. Jacobs, K. Mechtler

The paper benchmarks a micro-pillar array column against a conventional nano-flow HPLC column, showing improved sensitivity and peptide/protein identification in low-input proteomics.

bioRxiv · Jun 21, 2019Biochemistry