L. Martens

CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

The paper identifies CD163 and Tim-4 as markers for intestinal macrophages and shows TGF-β regulates their spatial distribution in different niches.

Trans-synaptic dwelling of SARS-CoV-2 particles perturbs neural synapse organization and function

The paper shows that SARS-CoV-2 exposure perturbs neural synapse organization and electrical activity by lodging at trans-synaptic interfaces.

Immunopeptidomics-based design of highly effective mRNA vaccine formulations against Listeria monocytogenes

The paper identifies Listeria monocytogenes epitopes using immunopeptidomics and shows that mRNA vaccines encoding these antigens induce strong immune responses and protection in mice.

An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia

The paper presents a comprehensive mass spectrometry-based atlas of histone posttranslational modifications in T-cell acute lymphoblastic leukemia cell lines, providing a reusable dataset for epidrug development.

C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100A8 and S100A9

This study identifies C/EBPδ as a key regulator of S100A8 and S100A9 expression through epigenetic mechanisms in monocytes, with implications for inflammatory diseases.

Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches

This study creates a spatial proteogenomic atlas of the liver across species, identifying conserved macrophage niches and their regulatory mechanisms.

Hodgkin and Huxley Opsin Model for Computationally Efficient Optogenetic Neurostimulation in Cells and Networks

The paper introduces a computationally efficient Hodgkin-Huxley-based model for optogenetic neurostimulation, showing improved speed and accuracy compared to traditional Markov models.

A simple approach for accurate peptide quantification in MS-based proteomics

This paper introduces a method to accurately quantify MS-ready peptides using a microfluidic UV/visible spectrophotometer, improving LC-MS/MS and protein quantification data consistency.

A well-ordered nanoflow LC-MS/MS approach for proteome profiling using 200 cm long micro pillar array columns

This paper introduces a long micro pillar array column for proteome profiling, showing improved protein identification and peak resolution compared to conventional columns.