Author

J. Orjala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. M. Crnkovic· 2 shared A. G. Ferreira· 1 shared A. Krunic· 1 shared A. S. Eustaquio· 1 shared H. Jeong· 1 shared H. Lee· 1 shared J. Diaz-Espinosa· 1 shared J. R. Lee· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

C. M. Crnkovic

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2 papers

Recent·Most cited

A novel family of nonribosomal peptides modulate collective behavior in Pseudovibrio bacteria isolated from marine sponges

L. P. Ioca, Y. Dai, S. Kunakom, J. Diaz-Espinosa, A. Krunic, C. M. Crnkovic, J. Orjala, L. M. Sanchez, A. G. Ferreira, R. G. Berlinck, A. S. Eustaquio

This study identifies a novel family of nonribosomal peptides, pseudovibriamides, produced by Pseudovibrio bacteria that modulate motility and biofilm formation, distinct from known surfactant lipopeptides.

bioRxiv · Dec 15, 2020Microbiology

Commensal gut bacteria convert the immunosuppressant tacrolimus to less potent metabolites

Y. Guo, C. M. Crnkovic, K.-J. Won, X. Yang, J. R. Lee, J. Orjala, H. Lee, H. Jeong

This study identifies gut bacteria, particularly Clostridiales, as a source of tacrolimus metabolism, producing less potent metabolites that may explain variable drug exposure after oral dosing.

bioRxiv · Oct 1, 2018Pharmacology & Toxicology