L. M. Sanchez

An Integrated Platform for in vivo Electrophysiology in Spatial Cognition Experiments

The paper introduces a flexible, cost-effective behavioral platform for spatial cognition research with software tools for precise neural event timing and reward delivery.

Metabolomics of bacterial-fungal pairwise interactions reveal conserved molecular mechanisms

The paper identifies fungal-produced small molecules in bacterial-fungal co-cultures, revealing their role in microbial interactions and highlighting fungi's contribution to microbiomes.

A gut commensal protist protects against virus-mediated loss of oral tolerance

This study identifies the protist Tritrichomonas arnold as a protector against virus-induced loss of oral tolerance to gluten, showing it reduces inflammation in dendritic cells and is underrepresented in celiac disease patients.

An integrated approach to protein discovery and detection from complex biofluids

This paper develops a mass spectrometry method to detect microproteins in vaginal lavages and identifies cystatin A as a potential biomarker for early ovarian cancer detection.

Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis.

This study characterizes plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastases, finding reduced EV numbers and increased PD-L1 in melanoma patients with brain metastases.

A novel family of nonribosomal peptides modulate collective behavior in Pseudovibrio bacteria isolated from marine sponges

This study identifies a novel family of nonribosomal peptides, pseudovibriamides, produced by Pseudovibrio bacteria that modulate motility and biofilm formation, distinct from known surfactant lipopeptides.

From iron to antibiotics: Identification of conserved bacterial-fungal interactions across diverse partners

This study identifies conserved bacterial-fungal interactions across 16 bacterial-fungal pairs, revealing that fungi modulate iron and biotin availability and produce uncharacterized antibiotics.

Addition of insoluble fiber to isolation media allows for increased metabolite diversity of lab-cultivable microbes derived from zebrafish gut samples

This study shows that adding insoluble fiber to isolation media increases microbial diversity and unique metabolite production from zebrafish gut microbes.

Biofilm inhibitor taurolithocholic acid alters colony morphology, specialized metabolism, and virulence of Pseudomonas aeruginosa

This study shows that taurolithocholic acid inhibits Pseudomonas aeruginosa biofilm formation and alters its specialized metabolism and virulence.

Detection of Ovarian Cancer Using Cells Sourced from a Local Microenvironment

The paper presents a MALDI-TOF MS method to detect ovarian cancer progression using vaginal fluid samples from tumor-bearing mice.

Coupling MALDI-TOF mass spectrometry protein and specialized metabolite analyses to rapidly discriminate bacterial function

This paper introduces IDBac, a method combining MALDI-TOF MS for protein and specialized metabolite analysis to rapidly distinguish bacterial function and phylogeny.