Author

J. Orth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. Schmidt· 1 shared J. Schoellkopf· 1 shared L. Hippchen· 1 shared N. Klugbauer· 1 shared R. Backofen· 1 shared R. Reuten· 1 shared S. Grossmann· 1 shared T. Mueller· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

G. Schmidt

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1 paper

Recent·Most cited

Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein1 (LRP1) as crucial cellular receptor

G. Schmidt, J. Schoellkopf, T. Mueller, L. Hippchen, T. Mueller, S. Grossmann, R. Reuten, R. Backofen, N. Klugbauer, J. Orth

The paper identifies LRP1 as a critical receptor for PMT toxin entry into cells using a CRISPR screen, showing its role in toxin binding and G protein activation.

bioRxiv · Aug 4, 2022Pharmacology & Toxicology