Widespread transcriptional scanning in the testis modulates gene evolution rates
B. Xia, Y. Yan, M. Baron, F. Wagner, D. Barkley, M. Chiodin, S. Y. Kim, D. L. Keefe, J. P. Alukal, J. D. Boeke, I. Yanai
The paper maps gene expression in human spermatogenesis and finds that expressed genes have fewer germline mutations, suggesting transcriptional scanning reduces DNA damage and influences gene evolution rates.
bioRxiv · Jan 22, 2019Evolutionary Biology