M. Chiodin

Integrating single-cell RNA-Seq with spatial transcriptomics in pancreatic ductal adenocarcinoma using multimodal intersection analysis

This study integrates single-cell RNA-Seq and spatial transcriptomics data from pancreatic cancer tissue to map cell type spatial distributions and infer tissue architecture.

Widespread transcriptional scanning in the testis modulates gene evolution rates

The paper maps gene expression in human spermatogenesis and finds that expressed genes have fewer germline mutations, suggesting transcriptional scanning reduces DNA damage and influences gene evolution rates.