Author

J. P. Dubey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:fungi (other)· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. P. Boyle· 2 shared S. L. Sokol· 2 shared Z. S. Wong· 2 shared A. S. Primack· 1 shared B. Martorelli Di Genova· 1 shared L. J. Knoll· 1 shared M. Tembo· 1 shared S. C. Nair· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

J. P. Boyle

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Author profile →

3 papers

Recent·Most cited

Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction

B. Martorelli Di Genova, S. K. Wilson, J. P. Dubey, L. J. Knoll

This paper identifies delta-6-desaturase activity as a determinant of species specificity for Toxoplasma gondii sexual reproduction, showing that feline intestinal lipid metabolism enables the sexual cycle while mice require dietary supplementation to achieve it.

bioRxiv · Jul 1, 2019Microbiology

Parasite manipulation of the host cell cycle as a means to block inflammatory signaling and promote intracellular replication

Z. S. Wong, S. L. Sokol, J. P. Dubey, J. P. Boyle

This study compares the host response and cell cycle effects of two parasites, finding that H. hammondi induces stronger host responses and cell cycle arrest than T. gondii, which suppresses the host's SASP response to enhance its own replication.

bioRxiv · May 1, 2019 · PreprintCell Biology

Hammondia hammondi has a developmental program in vitro that mirrors its stringent two host life cycle

S. L. Sokol, A. S. Primack, S. C. Nair, Z. S. Wong, M. Tembo, J. P. Dubey, S. K. Verma, J. P. Boyle

This study compares the in vitro developmental programs of Hammondia hammondi and Toxoplasma gondii, revealing distinct growth states and life cycle characteristics in H. hammondi.

bioRxiv · Jun 9, 2017Microbiology