Author

J. P. Ernest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

R. M. Savic· 2 shared A. A. Bauman· 1 shared A. Deitchman· 1 shared B. K. Podell· 1 shared C. Dide-Agossou· 1 shared E. Nuermberger· 1 shared F. Kaya· 1 shared G. T. Robertson· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

R. M. Savic

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Author profile →

2 papers

Recent·Most cited

Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses

N. D. Walter, J. P. Ernest, C. Dide-Agossou, A. A. Bauman, M. E. Ramey, K. Rossmassler, L. M. Massoudi, S. Pauly, R. Al Mubarak, M. I. Voskuil, F. Kaya, J. P. Sarathy, M. D. Zimmerman, V. Dartois, B. K. Podell, , G. T. Robertson

The paper shows that Mycobacterium tuberculosis in different lung microenvironments have distinct phenotypes and treatment responses in a mouse model.

bioRxiv · Feb 3, 2023 · PreprintMicrobiology

Translational predictions of phase 2a first-in patient efficacy studies for antituberculosis drugs

R. M. Savic, J. J. N. Goh, J. P. Ernest, N. Strydom, Q. Wang, R. C. van Wijk, N. Zhang, A. Deitchman, E. Nuermberger

The paper predicts clinical efficacy of antituberculosis drugs using preclinical PKPD data and translational pharmacology models to reduce phase 2a trial costs and failures.

bioRxiv · Jan 18, 2023Pharmacology & Toxicology