Author

J. Paulk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Burke· 1 shared A. Fazal· 1 shared A. Frommlet· 1 shared A. Godbole· 1 shared A. O. Frank· 1 shared A. T. Kedves· 1 shared B. Okram· 1 shared C. Be· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

A. Burke

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2 papers

Recent·Most cited

Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8

D. Remillard, N. A. Savage, A. T. Kedves, J. Paulk, X. Chen, F. J. Garcia, M. J. Romanowski, P. A. Horton, J. Murphy, M. Schirle, E. M. Harrington, M. B. Maxwell, H. T. Pham, I. Maksimovic, J. R. Thomas, W. C. Forrester

The paper identifies a novel interaction between BRD8 and the NuA4 complex using chemoproteomics and develops selective probes for BRD8.

bioRxiv · Feb 22, 2021Biochemistry

The Structural Basis of Indisulam-Mediated Recruitment of RBM39 to the DCAF15-DDB1-DDA1 E3 Ligase Complex

D. E. Bussiere, L. Xie, W. Shu, H. Srinivas, W. Shu, A. Burke, C. Be, J. Zhao, A. Godbole, D. King, R. G. Karki, V. Hornak, F. Xu, J. Cobb, N. Carte, , J. Paulk

This study determines the structure of the DCAF15-DDB1-DDA1-Indisulam-RBM39 complex, revealing how Indisulam promotes RBM39 degradation via a novel degron motif.

bioRxiv · Aug 16, 2019Biophysics

J. Paulk · henhao