Author

J. Paysant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Christopoulos· 1 shared C. J. Langmead· 1 shared J. Merlin· 1 shared L. T. May· 1 shared M. Feletou· 1 shared P. J. White· 1 shared P. M. Sexton· 1 shared P. Rueda· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Christopoulos

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1 paper

Recent·Most cited

Pharmacological insights into safety and efficacy determinants for the development of adenosine receptor biased agonists in the treatment of heart failure

P. Rueda, J. Merlin, S. Chimenti, M. Feletou, J. Paysant, P. J. White, A. Christopoulos, P. M. Sexton, R. J. Summers, W. N. Charman, L. T. May, C. J. Langmead

This study compares the safety and efficacy of A1R agonists, showing that biased agonism away from Ca2+ influx relative to cAMP improves safety but may not guarantee efficacy in heart failure.

bioRxiv · Jul 22, 2020Pharmacology & Toxicology