Molecular mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct proteoforms within the coupled positive and negative feedback circuits
Y. Xiang, M. Wang, S. Hu, L. Qiu, F. Yang, Z. Zhang, S. Yu, J. Pi, Y. Zhang
This study identifies the molecular mechanisms and post-translational modifications governing the generation of distinct Nrf1α/TCF11 proteoforms and their involvement in feedback circuits with regulatory proteins.
bioRxiv · Apr 12, 2018Biochemistry