Actin accumulates nesprin-2 at the front of the nucleus during confined cell migration
P. M. Davidson, A. Battistella, T. Dejardin, T. Betz, J. Plastino, B. Cadot, N. Borghi, C. Sykes
The paper shows actin redistributes nesprin-2 giant to the front of the nucleus during migration through narrow constrictions, contributing to nuclear pulling forces.
bioRxiv · Feb 14, 2020Cell Biology