Author

C. Sykes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Cadot· 2 shared C. Simon· 2 shared J. Plastino· 2 shared N. Borghi· 2 shared P. M. Davidson· 2 shared T. Betz· 2 shared T. Dejardin· 2 shared A. Allard· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

B. Cadot

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Validation of an LC-MS/MS Assay for the Simultaneous Determination of Bictegravir, Doravirine, and Raltegravir in Human Plasma

A. Schauer, C. Sykes, M. Cottrell, A. D. Kashuba

The paper validates an LC-MS/MS method to simultaneously measure Bictegravir, Doravirine, and Raltegravir in human plasma across a wide range.

bioRxiv · May 21, 2020Pharmacology & Toxicology

Actin accumulates nesprin-2 at the front of the nucleus during confined cell migration

P. M. Davidson, A. Battistella, T. Dejardin, T. Betz, J. Plastino, B. Cadot, N. Borghi, C. Sykes

The paper shows actin redistributes nesprin-2 giant to the front of the nucleus during migration through narrow constrictions, contributing to nuclear pulling forces.

bioRxiv · Feb 14, 2020Cell Biology

Actin shells control buckling and wrinkling of biomembranes

R. Kusters, C. Simon, R. Lopes Dos Santos, V. Caorsi, S. Wu, J.-F. Joanny, P. Sens, C. Sykes

This study shows how varying actin shell thickness in reconstituted systems controls membrane shape changes under volume reduction, revealing a transition between buckling and wrinkling.

bioRxiv · Sep 25, 2019Biophysics

LINC complexes are mechanotransducers that discriminate Epithelial-Mesenchymal Transition programs

T. Dejardin, P. S. Carollo, P. M. Davidson, C. Seiler, D. Cuvelier, B. Cadot, C. Sykes, E. R. Gomes, N. Borghi

This study shows LINC complexes sense mechanical tension and regulate β-catenin signaling differently during partial and complete EMT.

bioRxiv · Aug 22, 2019Cell Biology

Actin modulates shape and mechanics of tubular membranes

A. Allard, M. Bouzid, T. Betz, C. Simon, M. Abou-Ghali, J. Lemiere, F. Valentino, J. Manzi, F. Brochard-Wyart, K. Guevorkian, J. Plastino, M. Lenz, C. Campillo, C. Sykes

This study investigates how actin affects the shape and mechanical stability of tubular membranes by observing actin sleeve growth on preformed membrane tubes.

bioRxiv · Jul 23, 2019Biophysics