J. Q. Bettinger

This study introduces a method to measure methionine oxidation in mouse brains and finds that oxidation is consistent across individuals but not significantly altered with age.

The paper shows that oxidation rates of buried methionines correlate with protein folding stability, using E. coli and T. thermophilus proteomes to demonstrate this relationship.

This study develops a method to quantify methionine oxidation in the human proteome by isotopic labeling and validates it using artificial proteomes, identifying novel in vivo oxidation sites.

The paper quantifies protein folding stabilities in human cell extracts using methionine oxidation rates, identifying stable ontological subsets and showing stability impacts oxidation and TMAO effects.