Author

J. R. Castillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Garcia· 1 shared A. Yilma· 1 shared B. Shenkoya· 1 shared D. Quijada· 1 shared H. Bailey· 1 shared H. Harris· 1 shared M. Gopalakrishnan· 1 shared M. L. Gennaro· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Garcia

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2 papers

Recent·Most cited

Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice

J. R. Castillo, V. Guerrini, D. Quijada, S. Karanika, P. Neupane, H. Harris, A. Garcia, B. Shenkoya, A. Yilma, H. Bailey, R. Khan, M. Gopalakrishnan, M. L. Gennaro, P. C. Karakousis

This study evaluates two compounds that reduce triglyceride content in Mtb-infected macrophages but finds they do not reduce bacterial burden or inflammation in infected mice.

bioRxiv · Mar 6, 2024 · PreprintPharmacology & Toxicology

Wolbachia endosymbionts manipulate GSC self-renewal and differentiation to reinforce host fertility

S. L. Russell, J. R. Castillo, W. T. Sullivan

This paper shows that Wolbachia infection rescues fertility defects in mei-P26-deficient flies and restores gene expression, protein levels, and reproductive output.

bioRxiv · Dec 15, 2022 · PreprintEvolutionary Biology