M. Gopalakrishnan

Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice

This study evaluates two compounds that reduce triglyceride content in Mtb-infected macrophages but finds they do not reduce bacterial burden or inflammation in infected mice.

Spatio-temporal correlations between catastrophe events in a microtubule bundle: a computational study

This study uses simulations to show that microtubule catastrophe events in a bundle are correlated, with closer filaments showing stronger coupling and more frequent catastrophes.

Force Generation By Polymerizing Filaments Revisited: Diffusive Interaction Leads To Nonlinear Force-Number Scaling

The paper revisits force generation by polymerizing filaments, showing that diffusive interactions lead to nonlinear force-number scaling in bundled filaments.

Ultrasensitivity and Fluctuations in the Barkai-Leibler Model of Chemotaxis Receptors in Escherichia coli

This paper analyzes a stochastic version of the Barkai-Leibler chemotaxis model in E. coli, showing ultrasensitivity and noise characteristics in receptor activity.