DETECTION OF INCIPIENT PANCREATIC CANCER WITH NOVEL TUMOR-SPECIFIC ANTIBODIES IN MOUSE MODELS
T. E. Oni, C. Bautista, J. R. Merrill, J. A. C. M. Goos, K. D. Rivera, K. Miyabayashi, G. Biffi, L. Garcia, D. Plenker, H. Patel, E. Elyada, M. Samaritano, K. H. Yu, D. J. Pappin, M. G. Goggins, , D. A. Tuveson
This study develops tumor-specific antibodies for early detection of pancreatic cancer using PET imaging in mouse models, identifying two mAbs that bind to CEACAM6 variants in tumors.
bioRxiv · Sep 10, 2020 · PreprintCancer Biology