3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors
L. M. Badder, A. J. Hollins, B. Herpers, K. Yan, K. B. Ewan, J. R. Shone, D. A. Badder, M. Naven, K. Ashelford, R. Hargest, A. R. Clarke, C. Esdar, H.-P. Buchstaller, D. Wienke, L. S. Price, , T. Dale
This study uses 3D colorectal cancer organoids to assess responses to Tankyrase inhibitors, showing morphometric analysis can detect drug effects on cancer stem cells.
bioRxiv · Jul 18, 2019Cancer Biology