Author

J. R. T. Adolacion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

N. Varadarajan· 4 shared M. Fathi· 3 shared A. Mahendra· 2 shared A. Rezvan· 2 shared G. Romain· 2 shared M. Martinez-Paniagua· 2 shared X. An· 2 shared A. Aggarwal· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersImmunology

N. Varadarajan

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Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 28, 2022

Metabolic plasticity of T-cell therapies: multi-omic profiling of interacting human tumor-infiltrating lymphocytes and autologous tumor adoptive cell therapy

M. Martinez-Paniagua, C. Haymaker, J. Robinson…·N. Varadarajan

This study profiles the metabolic interactions between TILs and autologous tumor cells in ACT, finding that responder TILs are more efficient at fatty acid oxidation under starvation.

DOI 10.1101/2022.09.28.509590

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivFeb 11, 2022

Multidimensional single-cell analysis identifies a role of CD2-CD58 interactions for clinical antitumor T cell responses

G. Romain, P. Strati, A. Rezvan…·N. Varadarajan

This study identifies CD2-CD58 interactions as critical for CAR T cell persistence and antitumor responses in lymphoma patients.

DOI 10.1172/jci159402

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivDec 14, 2020

Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer

M. Fathi, R. Joseph, J. R. T. Adolacion…·N. Varadarajan

The paper develops a single-cell technique to profile exosome secretion in breast cancer cells and finds that non-metastatic cells secrete more exosomes, which correlates with better prognosis and immune infiltration.

DOI 10.3390/cancers13174397

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivJun 1, 2017

Beyond Autoantibodies: Biological Roles Of Human Autoreactive B Cells In Rheumatoid Arthritis Revealed By Whole Transcriptome Profiling

A. Mahendra, X. Yang, S. Abnouf…·N. Varadarajan

This study identifies novel roles of autoreactive B cells in RA through transcriptome profiling, revealing potential therapeutic targets and mechanisms.

DOI 10.1002/art.40772

humanbulk RNA-seq

𝕏 PostBluesky