J. Robinson

Spatial N-glycan rearrangement on α5β1 integrin nucleates galectin-3 oligomers to determine endocytic fate α

The paper identifies how spatial N-glycan rearrangements on α5β1 integrin nucleate galectin-3 oligomers, determining endocytic fate and retrograde trafficking.

No evidence of "social immune memory" in Acorn ants (Temnothoax nylanderi)

This study tests for social immune memory in acorn ants and finds no evidence, suggesting previous positive results may stem from sublethal infections rather than cognitive effects.

cMYC-mediated immune repression is reversed by inhibition of H3K9/H3K27 methylation maintenance

This study shows that inhibiting H3K27/H3K9 methylation maintenance reverses cMYC-mediated immune repression in cancer, improving survival in mouse models.

Endocisternal interfaces for minimally invasive neural stimulation and recording of the brain and spinal cord

This paper introduces a chronic endocisternal neural interface for minimally invasive brain and spinal cord stimulation and recording, demonstrating repositioning and explantation capabilities in a large animal model.

Cellular visualization of G-quadruplex RNA via fluorescence lifetime imaging microscopy

This paper introduces a new fluorescent probe, TOR-G4, for visualizing G-quadruplex RNA in cells using fluorescence lifetime imaging microscopy, distinguishing G4s from other structures without relying on intensity changes.

Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)

This study investigates KLHL16 mutations in GAN using patient-derived iPSCs, revealing dysregulated intermediate filaments and astrocytic pathology.

Metabolic plasticity of T-cell therapies: multi-omic profiling of interacting human tumor-infiltrating lymphocytes and autologous tumor adoptive cell therapy

This study profiles the metabolic interactions between TILs and autologous tumor cells in ACT, finding that responder TILs are more efficient at fatty acid oxidation under starvation.

Restoration and resilience to sea level rise of a salt marsh affected by dieback events in Charleston, SC

This study shows that salt marshes in Charleston, SC, have not fully recovered 10 years after dieback events, highlighting the need for restoration and climate change mitigation.

Syncollin secreted by activated human neutrophils targets bacteria

This study shows that syncollin, secreted by activated human neutrophils, interacts with bacterial peptidoglycan and coats E. coli in co-cultures, suggesting a role in host defense.

A high-throughput approach to identify reproductive toxicants among environmental chemicals using an in vivo evaluation of gametogenesis in budding yeast Saccharomyces cerevisiae

This study develops a high-throughput yeast assay to identify reproductive toxicants among environmental chemicals, finding 57 toxic chemicals and a significant association with mammalian toxicity.

Novel enhancers of guanylyl cyclase-A activity via allosteric modulation

The paper identifies small molecule allosteric enhancers of GC-A that increase ANP and BNP signaling without using known binding sites or mechanisms.

An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines

A bat sarbecovirus uses the same cell entry route as SARS-CoV-2 but escapes vaccine immunity, highlighting the need for broader vaccines.

Impedance scaling for gold and platinum microelectrodes

This paper investigates how impedance scales with electrode area for gold and platinum microelectrodes, finding that platinum impedance transitions from area-based to perimeter-based scaling below 10 microns.

3D printed cobalt-chromium-molybdenum porous superalloy with superior antiviral activity

This paper demonstrates 3D printed Co-Cr-Mo superalloy with 100% SARS-CoV-2 inactivation in 30 minutes, outperforming copper and silver.

Determining the Depth Limit of Bioluminescent Sources in Scattering Media

This study determines the depth limit of bioluminescent sources in scattering media, finding cellular resolution imaging possible at 5-10 mean free paths.

Modification of forests by people means only 40% of remaining forests have high ecosystem integrity

The paper quantifies global forest modification, finding 40.5% of remaining forests have high ecosystem integrity, mostly in specific regions, and highlights the need for policies to protect these areas.

Detecting and visualising the impact of heterogeneous evolutionary processes on phylogenetic estimates

The paper presents methods to detect and visualize the impact of heterogeneous evolutionary processes on phylogenetic estimates.

HLA class II polymorphism influences the immune response to protective antigen and susceptibility to Bacillus anthracis

This study identifies HLA class II polymorphism effects on CD4+ T cell responses to PA epitopes and susceptibility to Bacillus anthracis.

Cdc42 promotes Bgs1 recruitment for septum synthesis and glucanase localization for cell separation during cytokinesis in fission yeast.

Comparative pathway enrichment analysis in gastrointestinal cell lines Caco-2, HT-29, HEPG2, and colon fibroblasts using a custom expression panel for tight-junction and cytoskeletal regulatory genes.

The paper compares gene expression in gastrointestinal cell lines and fibroblasts to identify variations relevant to intestinal epithelial function using a custom panel of tight-junction and cytoskeletal genes.

Complete blood count with differential: An effective diagnostic for IBS subtype in the context of BMI?

The paper analyzes CBC-D data from a clinical cohort to identify potential biomarkers for IBS subtypes and BMI, finding significant associations but poor predictive performance.

Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 30-day timeline with Dexamethasone exposure.

The paper analyzes differential gene expression and gene-set enrichment in Caco-2 monolayers exposed to Dexamethasone over 30 days, revealing GC and time-associated transcriptional responses.