Author

M. Martinez-Paniagua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Fathi· 4 shared N. Varadarajan· 4 shared A. Rezvan· 3 shared X. An· 3 shared C. Bernatchez· 2 shared J. R. T. Adolacion· 2 shared S. A. Mani· 2 shared A. Amritkar· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

M. Fathi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Metabolic plasticity of T-cell therapies: multi-omic profiling of interacting human tumor-infiltrating lymphocytes and autologous tumor adoptive cell therapy

M. Martinez-Paniagua, C. Haymaker, J. Robinson, M. Harel, C. Creasy, J. R. T. Adolacion, X. An, M. Fathi, A. Rezvan, M. Kumar, A. Amritkar, S. E. Woodman, R. N. Amaria, T. Geiger, P. Hwu, , N. Varadarajan

This study profiles the metabolic interactions between TILs and autologous tumor cells in ACT, finding that responder TILs are more efficient at fatty acid oxidation under starvation.

bioRxiv · Sep 28, 2022 · PreprintImmunology

Integrated single-cell functional and molecular profiling of extracellular vesicle secretion in metastatic breast cancer

M. Fathi, M. Martinez-Paniagua, A. Rezvan, M. J. Montalvo, V. Mohanty, K. Chen, S. A. Mani, N. Varadarajan

The paper identifies a four-gene signature associated with EV secretion in breast cancer and links it to poor prognosis and immune evasion.

bioRxiv · Aug 13, 2022 · PreprintCancer Biology

T-cell potential for CD19-expressing malignancies revealed by multi-dimensional single-cell profiling

A. Rezvan, G. Romain, M. Fathi, D. Heeke, M. Martinez-Paniagua, X. An, I. N. Bandey, A. Saeedi, F. Sadeghi, K. Fousek, N. Puebla-Osorio, L. J. Cooper, C. Bernatchez, H. Singh, N. Ahmed, , N. Varadarajan

The paper identifies migration as a cell-intrinsic biomarker for CAR+ T cell efficacy in B-cell malignancies using multi-dimensional single-cell profiling.

bioRxiv · Jun 22, 2022Immunology

Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer

M. Fathi, R. Joseph, J. R. T. Adolacion, M. Martinez-Paniagua, X. An, K. Gabrusiewicz, S. A. Mani, N. Varadarajan

The paper develops a single-cell technique to profile exosome secretion in breast cancer cells and finds that non-metastatic cells secrete more exosomes, which correlates with better prognosis and immune infiltration.

bioRxiv · Dec 14, 2020Cancer Biology