Author

J. R. Weir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

D. Rousova· 2 shared F. Mueller· 2 shared G. Vader· 2 shared P. Janning· 2 shared V. Altmannova· 2 shared V. B. Raina· 2 shared A. Sarembe· 1 shared A. Schaeffler· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

D. Rousova

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Mer3 helicase protects early crossover intermediates from STR complex disassembly during meiosis

V. Altmannova, M. Firlej, F. Mueller, P. Janning, R. Rauleder, D. Rousova, A. Schaeffler, J. R. Weir

This study identifies a new Mer3 complex with Top3 and Rmi1 and shows Mer3 inhibits the STR complex's anti-recombination activity, promoting crossover formation during meiosis.

bioRxiv · Jun 27, 2022Biochemistry

Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

D. Rousova, V. Nivsarkar, V. Altmannova, S. K. Funk, V. B. Raina, D. Liedtke, P. Janning, F. Mueller, H. Reichle, G. Vader, J. R. Weir

This study identifies Mer2 as a keystone in meiotic DSB formation by linking it to chromatin and DSB factors through biochemical interactions.

bioRxiv · Jul 30, 2020Biochemistry

A meiosis-specific AAA+ assembly reveals repurposing of ORC during budding yeast gametogenesis

M. A. Villar-Fernandez, R. Silva, D. Pan, E. Weir, A. Sarembe, V. B. Raina, J. R. Weir, G. Vader

The paper shows that ORC interacts with Pch2 to form a meiosis-specific AAA+ complex, revealing ORC's repurposing in budding yeast gametogenesis.

bioRxiv · Apr 4, 2019Biochemistry