Single cell mutant selection for metabolic engineering of actinomycetes
A. Akhgari, B. Baral, A. Koroleva, V. Siitonen, D. P. Fewer, C. E. Melancon, J. Rahkila, M. Metsa-Ketela
This paper develops a single-cell sorting method to enhance metabolic engineering in actinomycetes by selecting high-performing mutants for drug discovery and industrial enzyme production.
bioRxiv · Jan 13, 2022Bioengineering