Oral administration of an anti-CfaE secretory IgA antibody protects against Enterotoxigenic Escherichia coli diarrheal disease in a non-human primate model
M. Stoppato, C. Gaspar, J. Regeimbal, G. Nunez, s. giuntini, M. A. Gawron, J. R. Pondish, J. C. Martin, M. Schneider, Z. A. Schiller, M. Klempner, L. A. Cavacini, Y. Wang
This study evaluates the efficacy of secretory IgA2 and dimeric IgA2 antibodies against ETEC in a non-human primate model, finding that oral SIgA2 significantly reduced diarrheal attack rates.
bioRxiv · Aug 28, 2019Immunology