Author

J. Rene Espinosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Collepardo-Guevara· 2 shared A. Aguirre· 1 shared A. R. Tejedor· 1 shared B. P. O'Hara· 1 shared C. Chauvet· 1 shared C. Sbai· 1 shared F. Brau· 1 shared I. ben-sahra· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

R. Collepardo-Guevara

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2 papers

Recent·Most cited

Cell BiologyCellPeer-reviewedJan 1, 2025

Mechano-dependent sorbitol accumulation supports biomolecular condensate

S. Torrino, W. Oldham, A. R. Tejedor…·T. BERTERO

The paper shows matrix stiffening promotes biomolecular condensation via sorbitol, a mechanosensitive metabolite, and demonstrates this in breast cancer.

DOI 10.1016/j.cell.2024.10.048

humanproteomics

BiochemistrybioRxivDec 26, 2022

Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation

K. Brown, P. Y. Chew, S. Ingersoll…·X. Ren

This study reveals the scaffold-client model of PRC1 condensate assembly through phase separation, showing how CBX2 acts as a scaffold and other subunits influence condensate properties and composition.

DOI 10.1016/j.celrep.2023.113136

experimental assaybiophysical modeling