Author

J. Ruelas Castillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Byrne· 1 shared A. Garcia· 1 shared A. Sher· 1 shared A. Yilma· 1 shared C. Vollmers· 1 shared D. L. Costa· 1 shared D. Quijada· 1 shared E. Pepper-Tunick· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

A. Byrne

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2 papers

Recent·Most cited

The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model

J. Ruelas Castillo, P. Neupane, S. Karanika, S. Krug, D. Quijada, A. Garcia, S. Ayeh, A. Yilma, D. L. Costa, A. Sher, N. Fotouhi, N. Serbina, P. C. Karakousis

This paper evaluates the adjunctive effect of the HO-1 inhibitor stannsoporfin in combination with a novel MDR-TB regimen in a murine model, showing reduced lung bacillary burden but no effect on microbiological relapse.

bioRxiv · Aug 9, 2023Microbiology

Horizontal transmission and recombination maintain forever young bacterial symbiont genomes

S. L. Russell, E. Pepper-Tunick, J. Svedberg, A. Byrne, J. Ruelas Castillo, C. Vollmers, R. Beinart, R. Corbett-Detig

The paper examines how horizontal transmission and recombination sustain genome size and genetic diversity in marine bacterial symbionts despite expected degradation.

bioRxiv · Apr 8, 2020Evolutionary Biology