Author

J. S. Bloom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Assay:whole-genome sequencing· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Organism:yeast· 2 Organism:C. elegans· 1

Frequent Co-Authors

L. Kruglyak· 3 shared D. H. W. Leighton· 1 shared E. R. Jerison· 1 shared G. Bruni· 1 shared H. Marquez· 1 shared J. Boocock· 1 shared J. Collins· 1 shared J. Mitchell· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersEvolutionary Biology

L. Kruglyak

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Author profile →

3 papers

Recent·Most cited

Divergent C. elegans toxin alleles are suppressed by distinct mechanisms

S. Zdraljevic, L. Walter-McNeill, G. Bruni, H. Marquez, J. Collins, D. H. W. Leighton, N. Alexander, J. S. Bloom, L. Kruglyak

The paper identifies a new TA system in C. elegans with divergent toxin alleles suppressed by distinct mechanisms, including piRNA-mediated silencing in the N2 haplotype.

bioRxiv · Apr 26, 2024Evolutionary Biology

Ancient balancing selection maintains incompatible versions of a conserved metabolic pathway in yeast

J. Boocock, M. J. Sadhu, J. S. Bloom, L. Kruglyak

The paper identifies ancient balancing selection maintaining incompatible galactose metabolic pathway variants in yeast, revealing a tradeoff between growth in galactose and glucose.

bioRxiv · Nov 4, 2019Evolutionary Biology

Genetic Variation In Adaptability And Pleiotropy In Budding Yeast

E. R. Jerison, S. Kryazhimskiy, J. Mitchell, J. S. Bloom, L. Kruglyak, M. M. Desai

The paper quantifies genetic variation in adaptability and pleiotropy in budding yeast offspring, finding that initial genotype affects adaptability and pleiotropy, with heritable differences arising from natural variation.

bioRxiv · Mar 29, 2017Evolutionary Biology