Author

E. R. Jerison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 3 Organism:yeast· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. M. Desai· 3 shared A. N. Nguyen Ba· 2 shared S. Kryazhimskiy· 2 shared S. R. Quake· 2 shared A. M. Phillips· 1 shared A. Moulana· 1 shared A. Rego-Costa· 1 shared C. W. Bakerlee· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersEvolutionary Biology

M. M. Desai

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Author profile →

5 papers

Recent·Most cited

Reference-Free Germline Immunoglobulin Allele Discovery from B CellReceptor Sequencing Data

I. Cvijovic, E. R. Jerison, S. R. Quake

This paper introduces grmlin, a reference-free method to detect germline immunoglobulin alleles from B cell receptor sequencing data, achieving better specificity than existing methods.

bioRxiv · Nov 25, 2023 · PreprintImmunology

Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations

M. S. Johnson, S. Gopalakrishnan, J. Goyal, M. E. Dillingham, C. W. Bakerlee, P. T. Humphrey, T. Jagdish, E. R. Jerison, K. Kosheleva, K. R. Lawrence, J. Min, A. Moulana, A. M. Phillips, J. C. Piper, R. Purkanti, , M. M. Desai

This study tracks phenotypic and molecular evolution in 205 yeast populations over 10,000 generations, revealing patterns of declining adaptability, mutation accumulation, and genetic parallelism.

bioRxiv · Oct 9, 2020Evolutionary Biology

Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo

E. R. Jerison, S. R. Quake

The paper shows that T cell motility variability arises from a coupling between speed and turning, observed across species and preserved under perturbations.

bioRxiv · Dec 28, 2019Biophysics

Chance and Necessity in the Pleiotropic Consequences of Adaptation for Budding Yeast

E. R. Jerison, A. N. Nguyen Ba, M. M. Desai, S. Kryazhimskiy

The paper evolves yeast populations in different environments and finds that pleiotropic effects of mutations are shaped by both deterministic factors and stochastic mutation accumulation.

bioRxiv · Nov 27, 2019Evolutionary Biology

Genetic Variation In Adaptability And Pleiotropy In Budding Yeast

E. R. Jerison, S. Kryazhimskiy, J. Mitchell, J. S. Bloom, L. Kruglyak, M. M. Desai

The paper quantifies genetic variation in adaptability and pleiotropy in budding yeast offspring, finding that initial genotype affects adaptability and pleiotropy, with heritable differences arising from natural variation.

bioRxiv · Mar 29, 2017Evolutionary Biology