Author

J. S. Fell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

J. B. Siegel· 3 shared A. J. Muchlinski· 1 shared A. Vater· 1 shared C. Duan· 1 shared C. Hou· 1 shared D. L. Davisson· 1 shared D. Risner· 1 shared E. Spang· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBioengineering

J. B. Siegel

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Author profile →

4 papers

Recent·Most cited

Furanoditerpenoid biosynthesis in the bioenergy crop switchgrass is catalyzed by an alternate metabolic pathway

A. J. Muchlinski, M. Jia, K. J. Tiedge, J. S. Fell, K. A. Pelot, L. Chew, D. L. Davisson, Y. Chen, J. Siegel, J. T. Lovell, P. Zerbe

This study identifies and characterizes five cytochrome P450 monooxygenases in switchgrass that catalyze an alternative pathway for furanoditerpenoid biosynthesis, bypassing the canonical class I diterpene synthase pathway.

bioRxiv · Mar 30, 2021 · PreprintPlant Biology

Techno-economic assessment of animal cell-based meat

D. Risner, F. Li, J. S. Fell, S. Pace, J. B. Siegel, i. Tagkopoulos, E. Spang

This study assesses the economic viability of animal cell-based meat using a model based on cellular metabolism and engineering conventions, identifying key cost factors and technical requirements for profitability.

bioRxiv · Sep 10, 2020Bioengineering

Computationally Guided Design of BCR-ABL Tyrosine Kinase Inhibitors

C. Duan, S. K. S. Chu, J. B. Siegel, J. S. Fell

The paper designs two new BCR-ABL tyrosine kinase inhibitors with predicted improved binding affinity over imatinib for advanced chronic myeloid leukemia treatment.

bioRxiv · Aug 20, 2020 · PreprintPharmacology & Toxicology

Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: Q22T, W123R, F155G, Y169M, W438D, V401A

C. Hou, P. Smith, J. Huang, J. S. Fell, P. Huang, A. Vater, J. B. Siegel

The paper quantifies thermal stability and catalytic efficiency of six β-glucosidase B mutants and adds the data to a dataset to improve Rosetta algorithms for protein engineering.

bioRxiv · Dec 23, 2019 · PreprintBiochemistry