Author

J. S. Lyons

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

C. W. Ward· 1 shared H. C. Joca· 1 shared J. M. Leser· 1 shared J. P. Stains· 1 shared K. M. Williams· 1 shared M. Hughes· 1 shared M. P. Srikanth· 1 shared N. R. Gould· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

C. W. Ward

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1 paper

Recent·Most cited

Disparate Bone Anabolic Cues Activate Bone Formation by Regulating the Rapid Lysosomal Degradation of Sclerostin Protein

N. R. Gould, K. M. Williams, H. C. Joca, O. M. Torre, J. S. Lyons, J. M. Leser, M. P. Srikanth, M. Hughes, R. J. Khairallah, R. A. Feldman, C. W. Ward, J. P. Stains

This study shows mechanical and hormonal cues promote bone formation by rapidly degrading sclerostin via lysosomes, challenging the previous view that sclerostin regulation is solely transcriptional.

bioRxiv · Oct 26, 2020Cell Biology