Author

J. Sabina

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Evolutionary Biology· 1

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. L. Stevens· 1 shared D. Soll· 1 shared H. Lee· 1 shared H. S. Kwok· 1 shared J.-T. Zhang· 1 shared K. Lee· 1 shared S. V. Melnikov· 1 shared X. Fu· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperEvolutionary Biology

D. L. Stevens

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1 paper

Recent·Most cited

Exploiting evolutionary trade-offs to combat antibiotic resistance

S. V. Melnikov, D. L. Stevens, X. Fu, H. S. Kwok, J.-T. Zhang, Y. Shen, J. Sabina, K. Lee, H. Lee, D. Soll

The paper demonstrates that antibiotic-resistant cells can be inhibited by exploiting fitness trade-offs using norvaline to target genetic mutations in leucyl-tRNA synthetase in tavaborole-resistant E. coli.

bioRxiv · Jan 20, 2020 · PreprintEvolutionary Biology