Author

J. Selich-Anderson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 5 Assay:ChIP-seq· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Taslim· 4 shared E. R. Theisen· 4 shared S. L. Lessnick· 4 shared I. A. Showpnil· 3 shared J. C. Crow· 3 shared M. A. Boone· 2 shared A. Bayanjargal· 1 shared B. D. Sunkel· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

C. Taslim

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

A. Bayanjargal, C. Taslim, I. A. Showpnil, J. Selich-Anderson, J. C. Crow, R. Zhou, S. L. Lessnick, E. R. Theisen

This study investigates the role of the DBD-4 helix in EWSR1::FLI1's binding to GGAA microsatellites, showing its importance in genome regulation and oncogenic transformation in Ewing sarcoma.

bioRxiv · Jan 31, 2024Cancer Biology

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma

I. A. Showpnil, J. Selich-Anderson, C. Taslim, M. A. Boone, J. C. Crow, E. R. Theisen, S. L. Lessnick

This study identifies how EWS/FLI fusion proteins alter chromatin structure and transcription in Ewing sarcoma, highlighting their role in reprogramming 3D chromatin to drive transcriptional changes.

bioRxiv · Sep 30, 2021Cancer Biology

Chromatin profiling reveals reorganization of lysine specific demethylase 1 by an oncogenic fusion protein

E. R. Theisen, J. Selich-Anderson, K. R. Miller, J. M. Tanner, C. Taslim, K. I. Pishas, S. Sharma, S. L. Lessnick

The paper shows EWS/FLI fusion protein alters LSD1 distribution and function, impacting enhancer landscapes and gene activation in Ewing sarcoma.

Epigenetics · Apr 3, 2021Peer-reviewedCancer Biology

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma

M. A. Boone, C. Taslim, J. C. Crow, J. Selich-Anderson, I. A. Showpnil, B. D. Sunkel, M. Wang, B. Z. Stanton, E. R. Theisen, S. L. Lessnick

This study identifies the specific FLI regions in EWS/FLI critical for oncogenic transformation in Ewing sarcoma, showing the DNA-binding domain and a carboxyl-terminal alpha-helix are essential for transcriptional regulation and tumorigenesis.

bioRxiv · Oct 29, 2020Cancer Biology

Dual BRD4 and AURKA Inhibition is Synergistic against MYCN-amplified and nonamplified Neuroblastoma

J. Felgenhauer, L. Tomino, J. Selich-Anderson, E. Bopp, N. Shah

This paper shows that combining BRD4 and AURKA inhibitors synergistically inhibits neuroblastoma cell viability and prolongs survival in xenograft models.

bioRxiv · Mar 5, 2018Cancer Biology