Author

J. Shohet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. D'oto· 1 shared A. Davidoff· 1 shared A. Decock· 1 shared A. Mullasseril· 1 shared A. Murphy· 1 shared A. P. Berbegall· 1 shared A. Schramm· 1 shared A. Van Goethem· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. D'oto

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The roles of DDR2 and substrate stiffness on cancer cell transcriptome and proliferation

T. Vessella, S. Xiang, C. Xiao, M. Stilwell, E. Rozen, J. Shohet, S. Zhou, Q. Wen

This study investigates how DDR2 and substrate stiffness affect cancer cell proliferation and transcriptome, revealing distinct regulatory mechanisms.

bioRxiv · Oct 29, 2023 · PreprintBiochemistry

KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

A. D'oto, J. Fang, H. Jin, B. Xu, S. Singh, A. Mullasseril, V. Jones, X. Von Butler, B. Cooke, D. Hu, J. Shohet, A. Murphy, A. Davidoff, J. YANG

This study shows KDM6B promotes oncogenic CDK4/6-pRB-E2F pathway activation in neuroblastoma by maintaining enhancer activity, and its inhibition correlates with poor patient survival.

bioRxiv · Jul 2, 2020Cancer Biology

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

F. Zeka, A. Van Goethem, K. Vanderheyden, F. Demuynck, T. Lammens, A. Decock, H. H. Helsmoortel, J. Vermeulen, R. Noguera, A. P. Berbegall, V. Combaret, G. Schleiermacher, G. Laureys, A. Schramm, J. H. Schulte, , J. Vandesompele

This study identifies 9 miRNAs associated with metastatic neuroblastoma by analyzing serum miRNome in patient cohorts and xenografted mice.

bioRxiv · Apr 27, 2018Cancer Biology