Author

G. Schleiermacher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Geoerger· 3 shared A. Bellini· 2 shared C. Pierre-Eugene· 2 shared D. Surdez· 2 shared H. Che· 2 shared I. Jimenez· 2 shared J. Bhalshankar· 2 shared L. Chesler· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

B. Geoerger

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4 papers

Recent·Most cited

Environment-Dependent Modes of Adaptive Evolution in Neuroblastoma: Plasticity as a Selectable Trait

C. Roux, S. Hamer, A. Shea, E. Chen, A. S. Sadr, C. English, A. Allo Anido, H. Che, B. Geoerger, L. Chesler, G. Schleiermacher, M. D. Morgan, A. Bruna

This study identifies three modes of plasticity in neuroblastoma that shape tumour evolution under selective pressures and therapy resistance.

bioRxiv · Dec 7, 2023 · PreprintCancer Biology

COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS.

E. Tucker, I. Jimenez, L. Chen, A. Bellini, C. Gorrini, E. Calton, Q. Gao, H. Che, E. Poon, Y. Jamin, B. Martins da Costa, K. Barker, S. Shrestha, C. Hutchinson, S. Dhariwal, , G. Schleiermacher

This study evaluates lorlatinib, an ALK inhibitor, in combination with chemotherapy or idasanutlin in preclinical neuroblastoma models, finding synergy in models with high ALK expression.

Clinical Cancer Research · Apr 3, 2023Peer-reviewedCancer Biology

Interplay between intrinsic reprogramming potential and microenvironment controls neuroblastoma cell plasticity and identity

C. Thirant, A. Peltier, S. Durand, A. Kramdi, C. Louis-Brennetot, C. Pierre-Eugene, A. Costa, A. Grelier, S. Zaidi, N. Gruel, I. Jimenez, E. Lapouble, G. Pierron, H. Brisse, A. Gauthier, , I. Janoueix-Lerosey

This study shows that neuroblastoma cells can switch between noradrenergic and mesenchymal identities through epigenetic reprogramming, influenced by both intrinsic factors and the microenvironment.

bioRxiv · Jan 7, 2021 · PreprintCancer Biology

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

F. Zeka, A. Van Goethem, K. Vanderheyden, F. Demuynck, T. Lammens, A. Decock, H. H. Helsmoortel, J. Vermeulen, R. Noguera, A. P. Berbegall, V. Combaret, G. Schleiermacher, G. Laureys, A. Schramm, J. H. Schulte, , J. Vandesompele

This study identifies 9 miRNAs associated with metastatic neuroblastoma by analyzing serum miRNome in patient cohorts and xenografted mice.

bioRxiv · Apr 27, 2018Cancer Biology