Author

J. Sikela

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Biology Disciplines

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Issaian· 1 shared A. Pacheco· 1 shared B. Vögeli· 1 shared J. Davis· 1 shared K. Hansen· 1 shared N. Anderson· 1 shared T. Nemkov· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

A. Issaian

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1 paper

Recent·Most cited

Proteolytic Activation of Human-specific Olduvai Domains by the Furin Protease

A. Pacheco, A. Issaian, J. Davis, N. Anderson, T. Nemkov, B. Vögeli, K. Hansen, J. Sikela

The paper shows human-specific Olduvai domains are cleaved by furin protease, suggesting they function as proproteins activated by this processing, linking their expansion to human brain evolution.

bioRxiv · Jul 6, 2021Evolutionary Biology