Author

A. Issaian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Hansen· 2 shared A. D'Alessandro· 1 shared A. Hay· 1 shared A. Pacheco· 1 shared B. Vögeli· 1 shared D. Roberti· 1 shared E. Z. Eisenmesser· 1 shared G. P. Page· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersEvolutionary Biology

K. Hansen

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2 papers

Recent·Most cited

Proteolytic Activation of Human-specific Olduvai Domains by the Furin Protease

A. Pacheco, A. Issaian, J. Davis, N. Anderson, T. Nemkov, B. Vögeli, K. Hansen, J. Sikela

The paper shows human-specific Olduvai domains are cleaved by furin protease, suggesting they function as proproteins activated by this processing, linking their expansion to human brain evolution.

bioRxiv · Jul 6, 2021Evolutionary Biology

The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality

A. Issaian, A. Hay, M. Dzieciatkowska, D. Roberti, S. Perrotta, Z. Darula, J. S. Redzic, M. P. Busch, G. P. Page, K. Hansen, E. Z. Eisenmesser, J. C. Zimring, A. D'Alessandro

This paper investigates the role of the N-terminus of band 3 in red blood cell metabolism and storage quality using genetic models and proteomic analyses, showing its impact on metabolic pathways and transfusion outcomes.

bioRxiv · Nov 30, 2020Biochemistry