Deletion of intestinal SHP impairs short-term response to cholic acid challenge in mice.
J. T. Nguyen, R. Riessen, T. Zhang, C. Kieffer, S. Anakk
This study shows that deleting SHP in the intestine of mice impairs their response to cholic acid, affecting bile acid levels and transporters without altering FXR mRNA.
bioRxiv · Sep 2, 2020Physiology