Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity
R. D. Grinshpon, S. Shrestha, J. Titus-McQuillan, P. T. Hamilton, P. D. Swartz, A. C. Clark
The paper reconstructs ancestral caspase proteins to identify evolutionary changes in substrate specificity networks.
bioRxiv · Aug 28, 2019Biochemistry