Author

P. D. Swartz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:non-human primate· 1 Assay:protein structure· 1 Organism:zebrafish· 1

Frequent Co-Authors

C. Clark· 2 shared P. T. Hamilton· 2 shared R. D. Grinshpon· 2 shared S. Shrestha· 2 shared A. C. Clark· 1 shared B. Dimos· 1 shared J. Titus-McQuillan· 1 shared J. Tung· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

C. Clark

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3 papers

Recent·Most cited

Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3

L. Yao, P. D. Swartz, P. Hamilton, C. Clark

This study shows that changes in hydrogen bonding near the S3 subsite of caspase-3 affect P4 amino acid selection, leading to relaxed specificity in zebrafish caspase-3a compared to caspase-6.

bioRxiv · Aug 7, 2020Biochemistry

Caspases from Scleractinian Coral Show Unique Regulatory Features

S. Shrestha, J. Tung, R. D. Grinshpon, P. D. Swartz, P. T. Hamilton, B. Dimos, L. Mydlarz, C. Clark

This study identifies and characterizes caspases from disease-sensitive and -resistant corals, revealing unique regulatory features and structural insights into their function.

bioRxiv · Apr 13, 2020Biochemistry

Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity

R. D. Grinshpon, S. Shrestha, J. Titus-McQuillan, P. T. Hamilton, P. D. Swartz, A. C. Clark

The paper reconstructs ancestral caspase proteins to identify evolutionary changes in substrate specificity networks.

bioRxiv · Aug 28, 2019Biochemistry