Author

J. Tsalikis

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Bianchi· 1 shared D. Arnoult· 1 shared D. J. Philpott· 1 shared H. N. Chau· 1 shared J. L. Gommerman· 1 shared J.-J. Chen· 1 shared L. V. Kalia· 1 shared M. Abdel-Nour· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. A. Bianchi

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1 paper

Recent·Most cited

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

M. Abdel-Nour, V. Ramaglia, A. A. Bianchi, J. Tsalikis, H. N. Chau, S. K. Kalia, L. V. Kalia, J.-J. Chen, D. Arnoult, J. L. Gommerman, D. J. Philpott, S. E. Girardin

This study shows that HRI enhances autophagic clearance of cytosolic protein aggregates when the UPS is inhibited, and its absence leads to aggregate accumulation and cytotoxicity in both cell and mouse models.

bioRxiv · May 12, 2020Cell Biology