Author

J. Varon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Y. Kim· 2 shared R. M. Baron· 2 shared A. Bholse· 1 shared A. J. Weissman· 1 shared B. A. Maron· 1 shared B. M. Baron· 1 shared C. B. Clish· 1 shared C. Beaulieu· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

E. Y. Kim

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Author profile →

3 papers

Recent·Most cited

Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis

D. R. Ziehr, F. Li, K. M. Parnell, N. M. Krah, K. J. Leahy, C. Guillermier, J. Varon, R. M. Baron, B. A. Maron, N. J. Philp, L. P. Hariri, E. Y. Kim, M. L. Steinhauser, R. S. Knipe, J. Rutter, W. Oldham

The paper shows that inhibiting lactate transporters MCT1 and MCT4 reduces myofibroblast differentiation and pulmonary fibrosis in vitro and in vivo.

bioRxiv · Apr 25, 2024Cell Biology

Identification and targeting of microbial putrescine acetylation in bloodstream infections

J. R. Mayers, J. Varon, R. R. Zhou, M. Daniel-Ivad, C. Beaulieu, A. Bholse, N. R. Glasser, F. M. Lichtenauer, J. Ng, M. Pinilla Vera, C. Huttenhower, M. A. Perrella, C. B. Clish, S. D. Zhao, R. M. Baron, E. P. Balskus

The paper identifies bacterially-derived N-acetylputrescine as a marker of severe gram-negative bloodstream infections and shows that inhibiting its synthesis reduces bacterial growth and antibiotic resistance.

bioRxiv · Sep 21, 2023 · PreprintMicrobiology

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

T. Tamura, C. Cheng, W. Chen, L. C. Merriam, M. Pinilla-Vera, J. Varon, P. C. Hou, P. R. Lawler, W. M. Oldham, R. R. Seethala, Y. Tesfaigzi, A. J. Weissman, B. M. Baron, F. Ichinose, K. M. Berg, , Immunology of Cardiac Arrest Network (I-CAN)

The paper uses single-cell transcriptomics to identify immune cell states and cytokine interactions linked to poor neurological outcomes after cardiac arrest.

bioRxiv · Apr 4, 2022Immunology