Author

J. W. C. Rodriguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

S. Bahmanyar· 2 shared H. Merta· 1 shared M. V. Airola· 1 shared S. Gao· 1 shared S. Lee· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

S. Bahmanyar

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2 papers

Recent·Most cited

BiochemistrybioRxivNov 20, 2023

Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology

S. Gao, J. W. C. Rodriguez, S. Bahmanyar, M. V. Airola

This study identifies CTDNEP1-NEP1R1 as a conserved membrane phosphatase complex that restricts ER expansion, with NEP1R1 activating CTDNEP1 through structural stabilization and substrate orientation.

DOI 10.1073/pnas.2321167121

humanstructural biology

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Cell BiologybioRxivJul 6, 2022

A membrane sensing mechanism couples local lipid metabolism to protein degradation at the inner nuclear membrane

S. Lee, H. Merta, J. W. C. Rodriguez, S. Bahmanyar

The paper shows that the inner nuclear membrane's lipid environment protects Sun2 from degradation by sensing diacylglycerol through an amphipathic helix, regulated by CTDNEP1 and lipin 1.

DOI 10.1083/jcb.202304026

proteomicsexperimental assay

𝕏 PostBluesky