Author

M. V. Airola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

S. Gao· 3 shared J. E. Burke· 2 shared K. D. Fleming· 2 shared S. Bahmanyar· 2 shared A. R. Thiam· 1 shared B. E. Moeller· 1 shared C. C. Weckerly· 1 shared C. Mao· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

S. Gao

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PILS-Nir1 is a novel phosphatidic acid biosensor that reveals mechanisms of lipid production

C. C. Weckerly, T. A. Rahn, M. Ehrlich, R. C. Wills, J. G. Pemberton, M. V. Airola, G. R. Hammond

The paper develops PILS-Nir1, a phosphatidic acid biosensor, and shows it detects PA dynamics in live cells with higher sensitivity than existing tools.

bioRxiv · Feb 28, 2024 · PreprintCell Biology

Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology

S. Gao, J. W. C. Rodriguez, S. Bahmanyar, M. V. Airola

This study identifies CTDNEP1-NEP1R1 as a conserved membrane phosphatase complex that restricts ER expansion, with NEP1R1 activating CTDNEP1 through structural stabilization and substrate orientation.

bioRxiv · Nov 20, 2023Biochemistry

Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage

J. W. Carrasquillo Rodriguez, O. Uche, S. Gao, S. Lee, M. V. Airola, S. Bahmanyar

This study shows that CTDNEP1's regulatory subunit NEP1R1 controls its degradation to regulate ER membrane synthesis via lipin 1, but not lipid droplet biogenesis.

bioRxiv · Oct 12, 2023Cell Biology

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Y.-M. Choi, D. Ajjaji, K. D. Fleming, P. P. Borbat, M. L. Jenkins, B. E. Moeller, S. Fernando, S. R. Bhatia, J. H. Freed, J. E. Burke, A. R. Thiam, M. V. Airola

The paper investigates how lipid composition, specifically phosphatidic acid and diacylglycerol, affects PLIN3 recruitment to membranes and LDs, revealing structural changes in the PAT domain.

bioRxiv · Nov 17, 2022Biochemistry

The middle lipin (M-Lip) domain is a new dimeric protein fold that binds membranes

W. Gu, S. Gao, H. Wang, K. D. Fleming, R. M. Hoffmann, J. W. Yang, N. M. Patel, Y. M. Choi, J. E. Burke, K. Reue, M. V. Airola

The paper identifies the M-Lip domain as a novel dimeric protein fold that binds membranes and is essential for lipin function.

bioRxiv · Mar 19, 2021Biochemistry

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases

J. K. Yi, R. Xu, L. M. Obeid, Y. A. Hannun, M. V. Airola, C. Mao

This study investigates the catalytic mechanism of ACER3, identifying key residues and demonstrating its Zn2+-dependent activity similar to other Zn-based amidases.

bioRxiv · Oct 13, 2018Biochemistry