Author

H. Merta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

S. Bahmanyar· 3 shared B. Paul· 2 shared W. M. Henne· 2 shared D. J. Needleman· 1 shared D. Needleman· 1 shared G. Danuser· 1 shared G. Dias do Vale· 1 shared H.-Y. Wu· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCell Biology

S. Bahmanyar

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Author profile →

5 papers

Recent·Most cited

Paraoxonase-like APMAP maintains endoplasmic reticulum-associated lipid and lipoprotein homeostasis

B. Paul, H. Merta, R. Ugrankar-Banerjee, M. Hensley, S. Tran, G. Dias do Vale, J. G. McDonald, S. A. Farber, W. M. Henne

This paper identifies APMAP as an ER-localized antioxidant that maintains lipid and lipoprotein homeostasis, with loss of APMAP causing ER stress, lipid droplet accumulation, and altered lipoprotein maturation across multiple organisms.

bioRxiv · Jan 26, 2024Cell Biology

Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration

H. Merta, T. Isogai, B. Paul, G. Danuser, W. M. Henne

The paper maps the human ER subdomain proteome, identifies CLMN as an ER-actin tether at focal adhesions, and shows it promotes cell migration by regulating actin dynamics and calcium signaling.

bioRxiv · Jan 24, 2024Cell Biology

Clustering of cortical dynein regulates the mechanics of spindle orientation in human mitotic cells

M. Anjur-Dietrich, V. G. Hererra, R. Farhadifar, H.-Y. Wu, H. Merta, S. Bahmanyar, M. Shelley, D. Needleman

This study measures forces on human mitotic spindles and shows that cortical dynein clustering determines spindle orientation mechanics.

bioRxiv · Sep 11, 2023 · PreprintCell Biology

A membrane sensing mechanism couples local lipid metabolism to protein degradation at the inner nuclear membrane

S. Lee, H. Merta, J. W. C. Rodriguez, S. Bahmanyar

The paper shows that the inner nuclear membrane's lipid environment protects Sun2 from degradation by sensing diacylglycerol through an amphipathic helix, regulated by CTDNEP1 and lipin 1.

bioRxiv · Jul 6, 2022Cell Biology

A CTDNEP1-lipin 1-mTOR regulatory network restricts ER membrane biogenesis to enable chromosome motions necessary for mitotic fidelity

H. Merta, J. W. Carrasquillo Rodriguez, M. I. Anjur-Dietrich, M. E. Granade, T. Vitale, T. E. Harris, D. J. Needleman, S. Bahmanyar

This study identifies a CTDNEP1-lipin 1-mTOR network that limits ER membrane biogenesis to enable proper chromosome movements and mitotic fidelity.

bioRxiv · Mar 2, 2021Cell Biology